Spectral confocal module coupled to an inverted microscope (4 objectives: 10x, 20x, 40x and 63x) equipped with three channels of spectral detection, AOBS (“Acousto-optical beam splitter”) and resonant scanner system. Argón, He/Ne and UV lasers. Incubation cabin for cells, which allows tracking of real-time processes.
ToF-SIMS 5 Time-of-flight secondary-ion mass spectrometry system (ION TOF ).
•• Sensitivity < 100 ppm.
•• Lateral resolution ~ 100 nm (extension of surface area analyzed).
•• Depth resolution ~ 1 nm (thickness of surface analyzed).
•• Identification of molecules up to 10000 amu.
K-Alpha X-ray photoelectron spectroscopy (XPS) system (Thermo):
•• Lateral resolution ~ 30-400 μm (extension of surface area analyzed).
•• Depth resolution ~ 10 nm (thickness of surface analyzed).
•• Depth profiles.
UVISEL ellipsometer (Horiba JovinYvon), range 190-2100 nm, based on phase modulation with cell for liquid media:
•• Measurement of thicknesses from 0.1 nm to 30 μm.
•• Measurement of thickness of various superimposed layers.
•• Simultaneous measurement of the proportion of various different materials present on a surface.
•• Estimation of the porosity as percentage of pores vs. deposited material.
•• Measurement of roughness of coating between 2.5 and 15 nm.
Temporarily OUT OF ORDERTAM III isothermal nanocalorimeter system including options for titration and perfusion. Also solution quasi-adiabatic calorimetry is available. (TA Instruments). Thermostatic bath: •• Working temperatures between 15 and 150 ºC •• Temperature scan < 2 ºC/h •• Stability: /- 10 μK on short timescales and /- 100 μK drift over 24 hours Calorimetric response: •• Precision better than 100 nW •• Reproducibility better than 1% •• Stability: < 10 nW on short timescales and < 40 nW drift over 24 hours Solution: •• Maximum temperature 80ºC •• Quasi-adiabatic mode of operation
Temporarily OUT OF ORDERUse of the system . X-ray photoelectron spectroscopy to measure quantitative elemental composition of surfaces (%) (except H and He).
Use of the system to measure the thickness of layers, and the composition, porosity and roughness of materials on a surface.
Tests in real time to measure:
·· Molecule-molecule interactions: Protein-protein, Receptor-ligand, Antibody-antigen, Biomaterial-molecule interactions, Biomaterial-cell interactions.
·· Microbial growth.
·· Cell metabolism.
Experiments of stability, growth,
etc, perfusion and dilution
Surface analysis of organic and inorganic materials (mass spectrum), map of chemical elements present in the surface of the sample (image), profile analysis shows sample analysis in depth.
Magnetometry on nanoparticles in solid form, ultra thin films, powders, liquids and even slurries:
Measurements of magnetic properties of materials:
Geophysical Research:
Biomedical Research:
